Maternal weight and conditions associated with fetal exposure to maternal blood or cervicovaginal secretions may diminish the efficacy of zidovudine chemoprophylaxis in terms of preventing perinatal human immunodeficiency virus type 1 transmission.
Prenatal diagnosis of fetal cytomegalovirus infection should include polymerase chain reaction assay in addition to viral culture, particularly for congenital infections after maternal recurrence.
In our series, autopsy determined the cause of perinatal death in 94% of cases and altered counseling or recurrence risk estimates in 26%.
Periodic or episodic deceleration and increased fetal heart rate variability during the late second trimester are associated with an increased risk of growth-restricted infants.
Atypical aneuploidy, observed in 1.0% of prenatal karyotypes, confers sufficient ambiguity to render counseling and prenatal decision making difficult, even in the absence of associated structural malformations.
Unexplained elevated serum alpha-fetoprotein or hCG levels increase the risk of adverse pregnancy outcome in women with low a priori risk but not in women with high a priori risk.
Physical and psychological health status change significantly during pregnancy and the puerperium.
Serious maternal morbidity resulting in prolonged delivery hospitalization or readmission is predicted by age over 32 years, black ethnicity, and primiparity.
Induced abortion may alter pregnancy duration in a subsequent pregnancy.
Administration of intravaginal 5-fluorouracil reduces recurrence of cervical intraepithelial neoplasia after standard surgery for high-grade lesions in human immunodeficiency virus–infected women.
Practice style may significantly affect the likelihood of receiving concomitant oophorectomy when postmenopausal women undergo hysterectomy.
Follicle-stimulating hormone concentrations are higher in women who have had hysterectomies, even if at least one ovary remains.
Arterial injury can be avoided during sacrospinous ligament suspension if sutures are placed along the superior border of the ligament more than 2.5 cm medial to the ischial spine, while avoiding full thickness.
Preclinical hyperdynamic circulatory alterations occur in preeclampsia and gestational hypertension, but preeclampsia is characterized by subsequent hemodynamic crossover to a low cardiac output, vasoconstricted state.
California state discharge data confirm a low rate of uterine rupture among women attempting vaginal birth after cesarean.
Obstetric providers often were unaware of abuse among maternal deaths from intimate partner homicide or depression among maternal deaths from suicide.
Oral misoprostol, though effective, results in significantly longer time from onset of induction to vaginal delivery than oxytocin when given for premature rupture of membranes.
Histologic confirmation of placental infection commonly is absent in cases of clinical diagnoses of maternal chorioamnionitis or possible neonatal sepsis.
Birth weight discordancy was associated with both antepartum fetal death and morbidity of prematurity in an analysis of 1370 consecutive twin gestations.
When a central nervous system abnormality is detected by prenatal ultrasound, magnetic resonance imaging findings may lead to altered diagnosis and patient counseling.
The risk of cystic fibrosis associated with echogenic fetal bowel and one detectable cystic fibrosis mutation is highest in populations with the lowest mutation detection rates.
Amnion-chorion separation that persists beyond 17 weeks' gestation is not necessarily a complication of amniocentesis and increases the risk of adverse perinatal outcomes.
The prostaglandin E subtype-1 receptor is nonuniformly localized on the amnion cell cytoplasmic membrane and is stimulated by inflammatory cytokines.
Lower levels of placental and decidual glutathione S-transferase pi might indicate a decreased operating capacity of the glutathione/glutathione S-transferase detoxification system in patients with preeclampsia compared with controls.
The sacrospinous ligament complex can be approached abdominally through the space of Retzius to provide vaginal vault support.
With the use of a computer and commercially available infusion pump, oxytocin infusion rates may be masked, which helps the study of induction and augmentation of labor.
Pregnancy is an important time to test for hepatitis C virus infection, a prevalent, potentially fatal virus that can be transmitted from mother to infant.
United States Medical Licensure Examination step 1 test scores correlate directly with obstetrics-gynecology final examination scores and can help identify students at risk of failure.
An ACOG-affiliated obstetrics and gynecology club for medical students succeeds because of strong collaboration between medical students and ACOG Fellows and Junior Fellows.
Letters to the Editor: COLPOSCOPY IN PREGNANCY: DIRECTED BRUSH CYTOLOGY COMPARED WITH CERVICAL BIOPSY Burton A. Krumholz, Richard Lieberman, Dennis M. O’Connor, Michael R. Henry Obstet Gynecol 1999 94: 1054-1055. [Full Text] [PDF]
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