The prevalence of hot flushes, aches, joint pain, stiffness, and depressed mood increases in the menopausal transition.
Laparoscopically guided minilaparotomy is able to reduce the intraperitoneal spillage rate when compared with laparoscopy in women with large cysts.
An alloimmune thrombocytopenia fetus having no prior affected sibling with an intracranial hemorrhage can be safely treated in utero, without cordocentesis, early in pregnancy.
A transfused volume of 20 mL/kg or higher in massive fetomaternal hemorrhage may cause severe perinatal complications.
Regional analgesia provides effective pain control for women maintained on methadone; postpartum opiate use is increased after cesarean delivery.
Ferric carboxymaltose given in large doses intravenously (IV) for postpartum anemia is tolerated better and corrects anemia faster and more reliably than ferrous sulfate given orally.
Focused ultrasound surgery for uterine leiomyomata results in a low number of additional procedures at 2 years and leads to symptomatic improvement and leiomyoma shrinkage.
Endocervical curettage is of questionable value in women younger than 40 years, but may be of diagnostic utility in older women undergoing colposcopy for equivocal or mildly abnormal cytology.
Age, stage, and lymph node involvement were significant factors for survival in women with vulvar melanoma.
Tinidazole administered orally provides effective treatment for bacterial vaginosis when rigorous requirements for cure are applied.
Transvaginal ultrasound cervical length and the gestational age at which it is measured are both important for estimation of risk of spontaneous preterm birth.
Birth defects are associated with preterm birth and low birth weight after controlling for multiple confounding factors, including shared risk factors and pregnancy complications.
Spontaneous very preterm births to mothers from more deprived areas are more likely to be associated with infection before birth.
Group prenatal care reduces preterm births, enhances psychosocial outcomes, and increases breastfeeding initiation at no added cost.
Goal attainment, satisfaction, and quality of life remain high in patients after colpocleisis surgery for pelvic organ prolapse.
In a prospective study of middle-aged women, adiposity and weight gain are associated with an increased risk developing urinary incontinence.
Low urethral closure pressure is the factor most strongly associated with de novo stress urinary incontinence followed by altered vesical neck mobility.
The methylenetetrahydrofolate reductase C677T polymorphism is a genetic marker for identifying women at increased risk of small for gestational age infants.
Maternal thyroid disease (most likely Graves' disease) or its treatment is associated with having an infant with craniosynostosis.
The Western maternal dietary pattern significantly contributes to cleft lip or cleft palate or both in the offspring.
Women who are human immunodeficiency virus infected and undergoing cesarean delivery are at increased risk for serious perioperative morbidity and at a 12-fold increased risk for maternal mortality.
Although triglycerides and total cholesterol are elevated in pregnant women on protease inhibitors compared with other regimens, lactate and gastrointestinal symptoms are not different.
First-trimester ultrasound assessment of the nasal bone may improve the performance of Down syndrome screening.
The evidence base of predictive markers (eg, clinical, sonographic, and biochemical) and preventative therapies (eg, progesterone) for recurrent preterm birth is reviewed.
Children with vaginal bleeding should be evaluated for anatomic, infectious, traumatic, and hormonal causes.
Abstracts: Abstracts Obstet Gynecol 2007 110: 421-424. [PDF]
Anterior colporrhaphy reinforced with tailored mesh prevents recurrence of prolapse of the anterior vaginal wall more frequently than traditional repair at 12-month follow-up.
Until further data on the safety and efficacy of transvaginal pelvic floor repair systems are obtained, they should be used cautiously.
The safety of electroconvulsive therapy use in pregnancy is uncertain.
Episiotomy scar tumor implantation from cervical cancer occurred 5 weeks after delivery.
Scar endometriosis should be considered in the differential diagnosis of a mass associated with a surgical scar, and awareness of the possibility of malignant change is required.
A life-threatening delayed hemolytic transfusion reaction with hyperhemolysis syndrome occurring after a precesarean prophylactic blood transfusion for sickle cell disease in pregnancy is described.
A pregnancy in a woman with hereditary hemorrhagic telangiectasia was successfully managed.
Pregnancy after conservative surgery and intraperitoneal chemotherapy may be achieved.
Carnitine deficiency due to a carnitine transporter defect can be managed successfully in pregnancy with exogenous carnitine supplementation.
After salpingo-oophorectomy for a mucinous cystadenoma, surgical site bleeding produced generalized placental ischemia and stillbirth.
The management of cold hemagglutinin disease in pregnancy includes keeping the patient warm and treating the anemia with warm packed red blood cell transfusion.
An infrequent case of nontransient neonatal alopecia, associated with mechanical extraction from the birth canal, and its surgical correction are described.
Nonpuerperal uterine inversion is rare and likely associated with malignancy in young women.
Doppler studies for fetal anemia should evaluate the equivalence of left and right middle cerebral artery peak systolic velocities to avoid unnecessary invasive testing in rare cases of discordancy.
Women with large pelvic varicosities in pregnancy are at risk for complications, but vaginal delivery may be safely achieved.
Polarized light and scanning electron microscopy identified talc in the pelvic lymph nodes of a woman with ovarian cancer and long-term cosmetic talc use.
Identifying pulmonary hypertension as a complication of portal hypertension in the pregnant patient requires a high index of clinical suspicion.
Pregnancy after incorrect transcervical hysteroscopic placement of microinserts in the myometrium is not detrimental to the mother or fetus.
Trastuzumab use in pregnancy is associated with oligohydramnios.
Peripheral neuropathy is a rare, potentially reversible, toxicity of nitrofurantoin, unreported in the obstetric and gynecologic literature, and commonly unrecognized by physicians who prescribe it.
Embolization combined with subtotal hysterectomy, leaving the adherent part of the placenta in situ, is an alternative approach for managing placenta percreta invading the bladder.
Acute menorrhagia from longstanding profound hypothyroidism may result in a severe life-threatening anemia.
Anastrozole therapy may induce regression of estrogen receptor positive metastatic uterine leiomyosarcoma.
A diagnosis of endometriosis should always be considered in premenopausal women who present with hemorrhagic ascites.
Reduction clitoroplasty corrects acquired clitoromegaly in adult women, with excellent cosmetic results and preservation of sexual function.
A woman presented with hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome at 17 weeks of gestation.
This case demonstrates the successful surgical correction of secondary amenorrhea resulting from traumatic separation of the uterine corpus from the cervix.
Surgical excision of inguinal endometriosis includes the entire extraperitoneal portion of the round ligament.
Aortic injury can occur while closing fascia with a laparoscopic fascial closure device.
Postpartum iliopsoas pyomyositis is a new, difficult to diagnose, and serious manifestation of the emerging pathogen, community-acquired, methicillin-resistant Staphylococcus aureus.
Pyometra is a serious complication of thermal balloon ablation with a likely multifactorial cause.
Maternal mirror syndrome is reversible with placement of a fetal peritoneal amniotic shunt to drain severe urinary ascites.
Uterine carcinosarcoma may be another cancer within the hereditary nonpolyposis colorectal cancer (HNPCC) spectrum, and the syndrome should be considered in persons with uterine carcinosarcoma and family history suspicious for HNPCC.
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