|
|
|
|
Group M versus group P*
|
Group M versus group A*
|
|
Group M (meclizine) (n = 108) |
Group P (placebo) (n = 107) |
Group A (no pretreatment) (n = 109) |
RR |
95% CI |
RR |
95% CI |
|
| Ever had nausea or vomiting |
51 (47) |
69 (64) |
70 (64) |
0.7 |
0.6, 0.9 |
0.7 |
0.6, 0.9 |
| Ever vomited |
5 (5) |
19 (18) |
14 (13) |
0.3 |
0.1, 0.6 |
0.4 |
0.1, 0.9 |
Highest severity of nausea |
| None |
57 (53) |
38 (36) |
39 (36) |
|
|
|
|
| Mild |
26 (24) |
29 (27) |
25 (23) |
|
|
|
|
| Moderate |
19 (18) |
16 (15) |
24 (22) |
|
|
|
|
| Severe (including vomiting) |
6 (6) |
24 (22) |
21 (19) |
|
|
|
|
|
| RR = relative risk; CI = confidence interval. Values in parentheses are percentages. |
| * Controlling for center. |
| Group M compared with group P, P = .002; group M compared with group A, P = .007. |
