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Isolated Multiple Bilateral Echogenic Papillary Muscles: A Unique Sonographic Feature of Trisomy 13

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine

Address reprint requests to: Joseph R. Wax, MD, Maine Medical Center, MMC Ob/Gyn Associates, 887 Congress Street, Suite 200, Portland, ME 04102; E-mail: waxj{at}mmc.org.

ABSTRACT

BACKGROUND: Echogenic papillary muscles are noted in 30% of fetuses with trisomy 13. All reported fetuses with trisomy 13 and echogenic papillary muscles have exhibited additional abnormal sonographic findings.

CASE: A 21.7-week fetus demonstrated three papillary echogenicities in each cardiac ventricle during ultrasound examination. Chromosomal analysis of amniocytes showed the karyotype 47,XX,+13.

CONCLUSION: Multiple bilateral papillary muscles may provide the only sonographic sign of fetal trisomy 13.