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Obstetrics & Gynecology 2001;98:1099-1103
© 2001 by The American College of Obstetricians and Gynecologists
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ORIGINAL RESEARCH

Reproductive Outcomes in Women With Congenital Uterine Anomalies Detected by Three-Dimensional Ultrasound Screening

Brigitte Woelfer, MD, Rehan Salim, MD, Saikat Banerjee, MD, Janine Elson, MD, Lesley Regan, MD, PhD and Davor Jurkovic, MD, PhD

From the Early Pregnancy & Gynaecology Assessment Unit, King’s College Hospital, and Recurrent Miscarriage Clinic, St Mary’s Hospital, London, United Kingdom.

Address reprint requests to: Davor Jurkovic, MD, PhD, Early Pregnancy and Gynaecology Assessment Unit, King’s College Hospital, Denmark Hill, London SE5 8RX United Kingdom; E-mail: davor.jurkovic{at}kcl.ac.uk.

OBJECTIVE: To determine reproductive outcomes in women with congenital uterine anomalies detected incidentally by three-dimensional ultrasound.

METHODS: We studied 1089 women with no history of infertility or recurrent miscarriage who were seen for a transvaginal ultrasound scan. They were screened for uterine abnormalities using three-dimensional ultrasound. We determined prevalence of miscarriage and preterm labor in women with normal and abnormal uterine morphology.

RESULTS: We found that 983 women had a normally shaped uterine cavity, 72 an arcuate, 29 a subseptate, and five a bicornuate uterus. Women with a subseptate uterus had a significantly higher proportion of first-trimester loss (Z = 4.68, P < .01) compared with women with a normal uterus. Women with an arcuate uterus had a significantly greater proportion of second-trimester loss (Z = 5.76, P < .01) and preterm labor (Z = 4.1, P < .01). There were no other significant differences in pregnancy outcomes between women with normal and abnormal uterine morphology.

CONCLUSION: This study shows the potential value of three-dimensional ultrasound and confirmed that women with congenital uterine anomalies were more likely to have adverse pregnancy outcomes than women with a normal uterus.




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