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Obstetrics & Gynecology 2001;98:923-925
© 2001 by The American College of Obstetricians and Gynecologists
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CASE REPORTS

Pancreatitis Secondary to Hyperparathyroidism During Pregnancy

Michael Dahan, MD and R. Jeffrey Chang, MD

Department of Reproductive Medicine, University of California at San Diego, San Diego, California

Address reprint requests to: Michael Dahan, MD, Department of Reproductive Medicine (0633), University of California at San Diego, 9500 Gilman Drive, San Diego, CA 92093; E-mail: mhdahan{at}ucsd.edu.

BACKGROUND: It has been suggested that magnesium can be used to reduce serum calcium levels seen with hyperparathyroidism during pregnancy, thus reducing maternal and fetal risk.

CASE: A young woman presented at 32 weeks’ gestation with abdominal pain from pancreatitis caused by hyperparathyroidism from a parathyroid adenoma. She was started on magnesium sulfate tocolysis for preterm labor. During treatment, serum parathyroid hormone was undetectable, but serum calcium and vitamin D-1,25 were elevated. When magnesium was discontinued, her vitamin D-1,25 was suppressed and the parathyroid hormone was elevated.

CONCLUSION: For some patients, because of persistent hypercalcemia, magnesium sulfate might not be a viable treatment option for hyperparathyroidism during pregnancy.






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