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ORIGINAL RESEARCH |
From the Department of Obstetrics and Gynecology, Chiang Mai University, Chiang Mai, Thailand.
Address reprint requests to: Teraporn Vutyavanich, MD, MSc Department of Obstetrics and Gynecology Faculty of Medicine Chiang Mai University Chiang Mai, 50200 Thailand E-mail: tvutyava{at}mail.med.cmu.ac.th
Objective: To determine the effectiveness of ginger for the treatment of nausea and vomiting of pregnancy.
Methods: Women with nausea and vomiting of pregnancy, who first attended an antenatal clinic at or before 17 weeks’ gestation, were invited to participate in the study. During a 5-month period, 70 eligible women gave consent and were randomized in a double-masked design to receive either oral ginger 1 g per day or an identical placebo for 4 days. Subjects graded the severity of their nausea using visual analog scales and recorded the number of vomiting episodes in the previous 24 hours before treatment, and again during 4 consecutive days while taking treatment. At a follow-up visit 7 days later, five-item Likert scales were used to assess the severity of their symptoms.
Results: All participants except three in the placebo group remained in the study. The visual analog scores of posttherapy minus baseline nausea decreased significantly in the ginger group (2.1 ± 1.9) compared with the placebo group (0.9 ± 2.2, P = .014). The number of vomiting episodes also decreased significantly in the ginger group (1.4 ± 1.3) compared with the placebo group (0.3 ± 1.1, P < .001). Likert scales showed that 28 of 32 in the ginger group had improvement in nausea symptoms compared with 10 of 35 in the placebo group (P < .001). No adverse effect of ginger on pregnancy outcome was detected.
Conclusion: Ginger is effective for relieving the severity of nausea and vomiting of pregnancy.
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