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ORIGINAL RESEARCH |
From the Department of Obstetrics and Gynecology, Poriya Hospital, Tiberias, Israel; and the Department of Obstetrics and Gynaecology, Sunnybrook and Womens College Health Sciences Centre, the Maternal, Infant and Reproductive Health Research Unit, Centre for Research in Womens Health, the Faculty of Nursing, and the Department of Obstetrics and Gynaecology, Mount Sinai Hospital, University of Toronto, Toronto, Canada.
Address reprint requests to: David Peleg, MD c/o Mary E. Hannah, MDCM Maternal, Infant and Reproductive Health Research Unit Room 751 University of Toronto 790 Bay Street Toronto, ON M5G 1N8 Canada E-mail: mary.hannah{at}utoronto.ca
Objective: To identify the significant predictors of cesarean delivery after prelabor rupture of membranes (PROM) at term.
Methods: In a multicenter study involving 72 institutions in six countries, 5041 women were randomized to induction of labor with oxytocin or prostaglandins or to expectant management. We did univariate and multivariate logistic regression analyses to determine the statistically significant independent predictors of cesarean delivery (P < .05).
Results: The following variables were found to be significantly associated with cesarean delivery: delivery in Israel, versus Canada (odds ratio [OR] 0.34); delivery in Australia, versus Canada (OR 1.93); nulliparity (OR 2.81); labor lasting more than 12 hours, versus less than 6 hours (OR 2.78); labor lasting 612 hours, versus less than 6 hours (OR 1.66); previous cesarean delivery (OR 2.75); epidural anesthesia (OR 2.66); clinical chorioamnionitis (OR 2.42); internal fetal heart rate monitoring (OR 2.19); birth weight of at least 4000 g (OR 2.07); use of oxytocin (OR 1.97); maternal age of at least 35 years (OR 1.44); latent period of at least 12 hours (OR 1.41); and meconium staining (OR 1.41).
Conclusion: Strong predictors of cesarean delivery after PROM at term were country of birth, nulliparity, long labor, previous cesarean delivery, and epidural anesthesia.
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