Obstetrics & Gynecology Track the topics, authors and articles important to you
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Obstetrics & Gynecology 1998;91:25-29
© 1998 by The American College of Obstetricians and Gynecologists
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Garzetti, G.
Right arrow Articles by Governa, M
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Garzetti, G.
Right arrow Articles by Governa, M

Articles

Decrease in peripheral blood polymorphonuclear leukocyte chemotactic index in endometriosis: role of prostaglandin E2 release

GG Garzetti, A Ciavattini, M Provinciali, M Amati, M Muzzioli, and M Governa

OBJECTIVE: To investigate the effect of disease on peripheral blood polymorphonuclear leukocyte chemotactic index and natural killer cell cytotoxicity and to provide additional information concerning the cell-mediated immune function in endometriosis. METHODS: Chemotactic index of peripheral blood polymorphonuclear leukocytes, natural killer cell activity, and plasma estradiol (E2) and plasma prostaglandin (PG) E2 levels were evaluated in 46 women who underwent laparoscopy or laparotomy for pelvic pain, infertility, and/or benign adnexal masses. RESULTS: The 20 women (43%) with endometriosis showed a decrease in peripheral blood polymorphonuclear leukocyte chemotactic index, related to advanced disease stage (P < .001). A significant inverse correlation was observed between plasma PGE2 levels and chemotactic index in stage III and IV endometriosis (r = -.73, P = .004). Similarly, natural cytotoxicity was decreased significantly with respect to the stage of endometriosis (P = .004) and related inversely to plasma PGE2 levels (r = -.74, P = .003). A direct relationship was observed between PGE2 and plasma E2 levels (r = .59, P = .006). CONCLUSION: Advanced endometriosis is associated with decreased peripheral blood polymorphonuclear leukocyte chemotactic index and natural killer cytotoxicity, which may be related to plasma PGE2 and E2 levels.


This article has been cited by other articles:


Home page
 J ANIM SCIHome page
M. C. Wulster-Radcliffe, R. C. Seals, and G. S. Lewis
Progesterone increases susceptibility of gilts to uterine infections after intrauterine inoculation with infectious bacteria
J Anim Sci, May 1, 2003; 81(5): 1242 - 1252.
[Abstract] [Full Text] [PDF]

Home page
 Hum ReprodHome page
J.-Y. Kwak, S.-W. Park, K.-H. Kim, Y.-J. Na, and K.-S. Lee
Modulation of neutrophil apoptosis by plasma and peritoneal fluid from patients with advanced endometriosis
Hum. Reprod., March 1, 2002; 17(3): 595 - 600.
[Abstract] [Full Text] [PDF]

Home page
 BloodHome page
G. B. Stefano, P. Cadet, C. Breton, Y. Goumon, V. Prevot, J. P. Dessaint, J.-C. Beauvillain, A. S. Roumier, I. Welters, and M. Salzet
Estradiol-stimulated nitric oxide release in human granulocytes is dependent on intracellular calcium transients: evidence of a cell surface estrogen receptor
Blood, June 15, 2000; 95(12): 3951 - 3958.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
G. B. Stefano, V. Prevot, J.-C. Beauvillain, C. Fimiani, I. Welters, P. Cadet, C. Breton, J. Pestel, M. Salzet, and T. V. Bilfinger
Estradiol Coupling to Human Monocyte Nitric Oxide Release Is Dependent on Intracellular Calcium Transients: Evidence for an Estrogen Surface Receptor
J. Immunol., October 1, 1999; 163(7): 3758 - 3763.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1998 by the American College of Obstetricians and Gynecologists.