Obstetrics & Gynecology Track the topics, authors and articles important to you
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Obstetrics & Gynecology 1996;87:564-567
© 1996 by The American College of Obstetricians and Gynecologists
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Phuapradit, W
Right arrow Articles by Lerdvuthisopon, N
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Phuapradit, W
Right arrow Articles by Lerdvuthisopon, N

Articles

Serum vitamin A and beta-carotene levels in pregnant women infected with human immunodeficiency virus-1

W Phuapradit, K Chaturachinda, S Taneepanichskul, J Sirivarasry, K Khupulsup, and N Lerdvuthisopon

OBJECTIVE: To determine if low levels of serum vitamin A and beta-carotene are present in pregnant women with human immunodeficiency virus-1 (HIV-1) infection. METHODS: Serum concentrations of vitamin A and beta-carotene were measured in 74 pregnant women seropositive for HIV-1 infection (17 with CD4 count below 200 cells/microliter) and in 148 pregnant seronegative controls in the first trimester. Comparisons were made between groups stratified by CD4 count. RESULTS: Compared with controls, women with HIV-1 infection and CD4 count below 200 cells/microliter exhibited 37% lower mean serum vitamin A levels (0.820 versus 1.308 micromol/L, P < .001) and 37% lower mean serum beta-carotene levels (1.486 versus 2.362 micromol/L, P < .001). Mean maternal age, parity, gestational age, hemoglobin levels, and body mass index at entry into the study did not differ significantly between the control and HIV-1 infection groups. In addition, serum vitamin A levels correlated significantly with the percentage of CD4 lymphocytes (r = 0.589, P < .001), CD4 count (r = 0.772, P < .001), and CD4 to CD8 ratio (r = 0.593, P < .001). Serum beta-carotene levels correlated with the percentage of CD4 lymphocytes (r = 0.407, P < .001), CD4 count (r = 0.614, P < .001), and CD4 to CD8 ratio (r = 0.434, P < .001). CONCLUSION: Compared with levels in uninfected women, serum vitamin A and beta-carotene are decreased in HIV-1-infected pregnant women in the first trimester with CD4 counts lower than 200 cells/microliter. These micronutrient concentrations also correlate with CD4 count.


This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
B. C Tohill, C. M Heilig, R. S Klein, A. Rompalo, S. Cu-Uvin, E. G Piwoz, D. J Jamieson, and A. Duerr
Nutritional biomarkers associated with gynecological conditions among US women with or at risk of HIV infection
Am. J. Clinical Nutrition, May 1, 2007; 85(5): 1327 - 1334.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Clin. Nutr.Home page
L. Kuhn, A. Coutsoudis, D. Trabattoni, D. Archary, T. Rossi, L. Segat, M. Clerici, and S. Crovella
Synergy between mannose-binding lectin gene polymorphisms and supplementation with vitamin A influences susceptibility to HIV infection in infants born to HIV-positive mothers.
Am. J. Clinical Nutrition, September 1, 2006; 84(3): 610 - 615.
[Abstract] [Full Text] [PDF]

Home page
 J Int Assoc Physicians AIDS Care (Chic Ill)Home page
N. Singhal and J. Austin
A Clinical Review of Micronutrients in HIV Infection
J Int Assoc Physicians AIDS Care (Chic Ill), April 1, 2002; 1(2): 63 - 75.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1996 by the American College of Obstetricians and Gynecologists.