| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Articles |
OBJECTIVE: To measure blood gases in uterine venous blood and maternal and fetal blood from the placenta, and to characterize gas exchange in the intervillous space. METHODS: Blood gas measurements were performed immediately after collecting placental and uterine blood from the subchorial and marginal lakes, from the chorionic vein and artery in the placenta in utero, and from the uterine vein during 12 cesarean deliveries. RESULTS: The mean oxygen pressure (PO2) values of the chorionic vein and subchorial lake were 28.7 +/- 6.0 and 29.9 +/- 7.5 mmHg, respectively, with a difference of 1.2 mmHg. The individual data for PO2 of the chorionic vein exceeded those of the subchorial lake in five subjects and were almost equal in two of the 12 subjects. The mean values of carbon dioxide pressure (PCO2) and bicarbonate were greater in the chorionic vein than in the subchorial lake, but the mean pH values were the same in the two groups. The mean values of blood gas analysis were not different between subchorial and marginal lakes with similar blood composition. The mean PO2 of the uterine vein in ten subjects was 45.9 mmHg, significantly higher than that of the subchorial lake. CONCLUSIONS: The human placenta may be defined as a multivillous model with a high degree of oxygen transfer. Arteriovenous anastomoses are suspected in the pregnant uterus beyond 37 weeks' gestation. Subchorial and marginal lakes contain similar admixed blood, which circulates and performs gas exchange.
This article has been cited by other articles:
|
|
 |
|
  L. Belkacemi, S. A. Bainbridge, M. A. Dickinson, G. N. Smith, and C. H. Graham Glyceryl Trinitrate Inhibits Hypoxia/Reoxygenation-Induced Apoptosis in the Syncytiotrophoblast of the Human Placenta: Therapeutic Implications for Preeclampsia Am. J. Pathol., March 1, 2007; 170(3): 909 - 920. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. A. Bainbridge, L. Belkacemi, M. Dickinson, C. H. Graham, and G. N. Smith Carbon Monoxide Inhibits Hypoxia/Reoxygenation-Induced Apoptosis and Secondary Necrosis in Syncytiotrophoblast Am. J. Pathol., September 1, 2006; 169(3): 774 - 783. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Padavala, N. Pope, P. Beker, and I. Crocker An Imbalance Between Vascular Endothelial Growth Factor and its Soluble Receptor in Placental Villous Explants of Intrauterine Growth-Restricted Pregnancies Reproductive Sciences, January 1, 2006; 13(1): 40 - 47. [Abstract] [PDF]
|
|
|
|
 |
|
 S. Ahmad and A. Ahmed Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in Preeclampsia Circ. Res., October 29, 2004; 95(9): 884 - 891. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I. P. Crocker, D. M. Tansinda, C. J.P. Jones, and P. N. Baker The Influence of Oxygen and Tumor Necrosis Factor-{alpha} on the Cellular Kinetics of Term Placental Villous Explants in Culture J. Histochem. Cytochem., June 1, 2004; 52(6): 749 - 757. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T.-H. Hung, J. N. Skepper, D. S. Charnock-Jones, and G. J. Burton Hypoxia-Reoxygenation: A Potent Inducer of Apoptotic Changes in the Human Placenta and Possible Etiological Factor in Preeclampsia Circ. Res., June 28, 2002; 90(12): 1274 - 1281. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
