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From the Child Development Center, Department of Pediatrics, Rhode Island Hospital, Brown University Program in Medicine, Providence, Rhode Island
Abstract
Menstrual histories were obtained from 51 females with Down syndrome between the ages of 10–27 years. The average age at onset of menstruation of girls in our study was 12 years, 6 months. Seventy-six percent of them had regular menstrual cycles with an average length of menstrual flow of 4 days, and most menstrual cycles lasted 25–30 days. Eight of the women with regular menstrual cycles provided 26 basal body temperature charts. When basal body temperatures were graphed using the smoothed-curve technique, 88.5% had biphasic curves indicative of an ovulatory pattern.
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