HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by van der LINDEN, P. J. Q. Articles by van KOOY, R. J. Search for Related Content PubMed PubMed Citation Articles by van der LINDEN, P. J. Q. Articles by van KOOY, R. J.

Retrograde Ejaculation: Successful Treatment With Artificial Insemination

From the Department of Obstetrics and Gynecology, Academic Hospital, State University Utrecht, Utrecht, The Netherlands

Abstract

Retrograde ejaculation is characterized by aspermia or oligospermia and results from an incompetent bladder neck, often due to a dysfunction of the internal sphincter. In almost 3 years, eight couples who suffered from infertility due to retrograde ejaculation were treated with inseminations with spermatozoa gained from the urine. Ovulation was predicted on the basis of blood LH levels. The urinesemen sample was collected in 100 mL of Hepes medium and 5 mL 1% human albumin (pH 7.4). After centrifuging, the remaining sperm pellet was dispersed on a Percol gradient. After centrifuging and resuspending, followed by two washing procedures with Ham's F-10 and human albumin 1%, the remaining sample was used for intrauterine insemination. Twelve pregnancies were thus achieved; two women became pregnant twice and one three times. The pregnancy rate per cycle was 44.4%. In seven couples, pregnancy was achieved within three cycles. Four pregnancies ended in spontaneous abortion and five ended in the birth of a healthy child; three pregnancies were continuing at the time of writing. Retrograde ejaculation can be treated successfully with inseminations using spermatozoa obtained from urine. It seems important to collect the urinesemen sample in a buffered medium and to time the insemination on the basis of the LH surge.

This article has been cited by other articles:

				D. M. Green Fertility and Pregnancy Outcome after Treatment for Cancer in Childhood or Adolescence Oncologist, June 1, 1997; 2(3): 171 - 179. [Abstract] [Full Text] [PDF]

				S. S. Howards Treatment of Male Infertility N. Engl. J. Med., February 2, 1995; 332(5): 312 - 317. [Full Text] [PDF]