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Obstetrics & Gynecology 1990;75:486-489
© 1990 by The American College of Obstetricians and Gynecologists
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EARLY DETECTION OF CAUDAL REGRESSION SYNDROME WITH TRANSVAGINAL SCANNING

Laxmi Baxi, MD, Wendy Warren, MD, Margaret H. Collins, MD and Ilan E. Timor-Tritsch, MD

From the Divisions of Maternal-Fetal Medicine and Pathology, Departments of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University and Sloane Hospital for Women at Columbia Presbyterian Medical Center, New York, New York

Abstract

High-resolution transvaginal ultrasonography may recognize structures in the first- and early second-trimester fetus. In a patient with pregestational diabetes, caudal regression syndrome in the fetus was diagnosed using transvaginal ultrasonography. At 9 weeks of gestation, a shortening of the crown-rump length and a protuberance of the lower spine suggested caudal regression syndrome. By 17 weeks of gestation, the diagnosis was made with certainty. The transvaginal approach has changed the role of first-trimester ultrasound in the diabetic pregnancy. We suggest that transvaginal ultrasonography be used for purposes of accurate dating and for early detection of diabetic embryopathy, particularly in patients with poor periconceptional glycemic control.







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