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Obstetrics & Gynecology 1989;74:786-788
© 1989 by The American College of Obstetricians and Gynecologists
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Does Preoperative Serum Squamous Cell Carcinoma Antigen Level Predict Occult Extracervical Disease in Patients With Stage Ib Invasive Squamous Cell Carcinoma of the Cervix?

BRUCE PATSNER, MD, JAMES W. ORR, Jr, MD and TARA ALLMEN, MS

From the Department of Obstetrics and Gynecology, State University of New York at Stony Brook School of Medicine, Stony Brook, New York; and the Watson Clinic, Lakeland, Florida

Abstract

Preoperative serum squamous cell carcinoma antigen levels were obtained from 65 patients with International Federation of Gynecology and Obstetrics stage Ib invasive squamous cervical cancer before planned radical hysterectomy to determine whether elevated squamous cell carcinoma antigen levels (greater than 2.5 ng/mL) predicted occult extracervical extension of disease. Although the specificity of a normal level was good (0.91), the sensitivity of an elevated level was only 0.68. Not all patients with nodal metastases had elevated serum squamous cell carcinoma antigen levels; in particular, no patient with occult para-aortic nodal disease had elevated serum squamous cell carcinoma antigen. (Obstet Gynecol 74:786, 1989)




This article has been cited by other articles:


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 Obstet GynecolHome page
B. Patsner, L. R. Duska, T. Toth, and A. Goodman
FERTILITY OPTIONS FOR PATIENTS WITH STAGES IA2 AND IB CERVICAL CANCER: PRESENTATION OF TWO CASES AND DISCUSSION OF TECHNICAL AND ETHICAL ISSUES
Obstet. Gynecol., March 1, 1999; 93(3): 474 - 474.
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Copyright © 1989 by the American College of Obstetricians and Gynecologists.