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From the Department of Social and Administrative Health Sciences, University of California, Berkeley, the Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, and the Departments of Reproductive Medicine and Community and Family Medicine, University of California, San Diego.
This study examined the relationship between maternal weight gain and preterm delivery in 2163 women who participated in the Prenatal Nutrition Project at the University of California, San Diego between 1978–1986. Multivari-ate analysis of the data indicated that the risk of spontaneous preterm birth increased 60% in women with a low rate of weight gain (less than 0.27 kg/week) compared with those with an average rate (0.27–0.52 kg/week). Women with a low rate of gain were more than twice as likely to experience a preterm delivery as those with a high gain (higher than 0.52 kg/week); the odds ratio was 2.54 and 95% confidence interval was 1.49, 4.88. This difference in weight gain appeared after 20 weeks' gestation.
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