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Obstetrics & Gynecology 1989;74:347-350
© 1989 by The American College of Obstetricians and Gynecologists
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Does Prolonged Preterm Premature Rupture of the Membranes Predispose to Abruptio Placentae?

R. GONEN, MD, M E HANNAH, MD, FRCS(C) and J E MILLIGAN, MD, FRCS(C)

From the Regional Perinatal Unit, Department of Obstetrics and Gynecology, Women's College Hospital, Toronto, Ontario, Canada

Abstract

The association between prolonged preterm premature rupture of the membranes and abruptio placentae was investigated in a case-control study. The incidence of abruptio placentae among 143 women with singleton pregnancies at less than 34 weeks ' gestation who had ruptured membranes for at least 24 hours was 5.6%, significantly higher than the 1.4% observed among 143 randomly selected controls without preterm rupture of the membranes (P <.05). Among patients with prolonged preterm premature rupture of the membranes, those who experienced vaginal bleeding before the onset of labor had a significantly higher risk for abruptio placentae than women who did not bleed (24 versus 2.5%; P <.001). Regardless of the mechanism by which this association is produced, the clinician should be aware of this potential complication, especially in patients who have recurrent bleeding episodes during the period of expectant management




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 Obstet GynecolHome page
C. V. Ananth, Y. Oyelese, N. Srinivas, L. Yeo, and A. M. Vintzileos
Preterm Premature Rupture of Membranes, Intrauterine Infection, and Oligohydramnios: Risk Factors for Placental Abruption
Obstet. Gynecol., July 1, 2004; 104(1): 71 - 77.
[Abstract] [Full Text] [PDF]


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Copyright © 1989 by the American College of Obstetricians and Gynecologists.