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Previous Intra-Amniotic Infection as a Risk Factor for Subsequent Peripartal Uterine Infections

From the Department of Obstetrics and Gynecology, University of Texas Health Science Center at San Antonio, San Antonio, Texas

Abstract

The risk of recurrent intra-amniotic infection was assessed in 76 women with a previous pregnancy complicated by intra-amniotic infection. Recurrent intra-amniotic infection occurred in five (6.6%), not significantly different from the incidence of 4.4% in a comparison population. When controlled by logistic regression for the increased cesarean section rate in the group with previous intra-amniotic infection, the incidence of endometritis was not significantly different between the groups. After eliminating nulliparas and patients who did not undergo labor, the incidence of intra-amniotic infection in patients with previous infections was not significantly increased over the comparison group. Those patients who did develop recurrent intra-amniotic infection had significantly longer labors (P<.001), duration of ruptured membranes (P=.002), and duration of internal monitoring (P<.001), and an increased number of vaginal examinations (P<.001). (Obstet Gynecol 74:299, 1989)

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