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Obstetrics & Gynecology 1987;69:43-46
© 1987 by The American College of Obstetricians and Gynecologists
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Atypical Squamous Cells in Papanicolaou Smears

GREGORY L. DAVIS, MD, ENRIQUE HERNANDEZ, MD, JANE L. DAVIS, BS, RN and KUNIO MIYAZAWA, MD

Department of Obstetrics and Gynecology, Tripler Army Medical Center, Honolulu, Hawaii.

Between 1980 and 1984, 406 patients were referred to Tripler Army Medical Center's cervical clinic for the evaluation of atypical squamous cells in a Papanicolaou smear. Their evaluation included repeating the smear, colposcopy in all cases, colposcopically directed biopsies, and/or endocervical curettage in 70%. The results of the repeat Papanicolaou smear in 400 patients were 274 (68.5%) negative, 77 (19%) atypical squamous cells, 40 (10%) cervical intraepithelial neoplasia (CIN) 1, seven (2%) CIN 2, and two (0.5%) CIN 3. No invasive cancer was detected. Dysplasia was documented histopathologically in 18.7%, but a repeat smear was reported as negative in 10.9% of patients with biopsyproven dysplasia. A Papanicolaou smear report of atypical squamous cells should not be considered normal, and further evaluation of the patient is required. If colposcopy is impractical, serial follow-up smears are recommended.




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