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Obstetrics & Gynecology 1986;68:S80-S83
© 1986 by The American College of Obstetricians and Gynecologists
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Ovarian Dysgerminoma

Immunocytochemical Localization of Human Chorionic Gonadotropin in the Germinoma Cell Cytoplasm

THOMAS J. MULLIN, MD and MOHAMAD R. LANKERANI, MD

From the Departments of Obstetrics and Gynecology, and Pathology, Cleveland Metropolitan General Hospital, Case-Western Reserve University, Cleveland, Ohio.

Abstract

A case of a pure ovarian dysgerminoma is reported in which the tumor was devoid of syncytiotrophoblastic giant cells, yet it produced human chorionic gonadotropin (hCG). Immunocytochemical studies localized the hCG in the germinoma cell cytoplasm, suggesting that these cells were the site of production.






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Copyright © 1986 by the American College of Obstetricians and Gynecologists.