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Obstetrics & Gynecology 1984;64:351-352
© 1984 by The American College of Obstetricians and Gynecologists
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Fetal Growth Delay and Maternal Hemoglobin A1c in. Early Diabetic Pregnancy

JAN FOG PEDERSEN, MD, LARS MOSLSTED-PEDERSEN, MD and HENRIK B. MORTENSEN, MD

From the Department of Obstetrics and Gynecology, Rigshospitalet, Ultrasound Laboratory, and the Department of Pediatrics, Glostrup Hospital, University of Copenhagen, Denmark.

Abstract

Forty insulin-dependent diabetic women in the first trimester of pregnancy were studied. Fetal crown-rump length was measured by ultrasound and related to maternal hemoglobin A1c. Thirty mothers with normal size fetuses had an average hemoglobin A1c level of 7.8%. Ten mothers had fetuses that were smaller than normal (equivalent to eight to 14 days less growth) and also had higher hemoglobin A1c, 8.9% (P < .05), indicating a more poorly controlled diabetes. Careful metabolic compensation in very early diabetic pregnancy should therefore be attempted to prevent induction of early fetal growth delay.




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H M Gardiner, L Pasquini, J Wolfenden, E Kulinskaya, W Li, and M Henein
Increased periconceptual maternal glycated haemoglobin in diabetic mothers reduces fetal long axis cardiac function
Heart, August 1, 2006; 92(8): 1125 - 1130.
[Abstract] [Full Text] [PDF]




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