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Uterine Endolymphatic Stromal Myosis

A Collaborative Study

Departments of Gynecologic Oncology, and Biostatistics, Roswell Park Memorial Institute, Buffalo, New York; Department of Gynecology, The Cleveland Clinic, Cleveland, Ohio; and the Department of Gynecology, M. D. Anderson Tumor Institute, Houston, Texas.

Fifty-two cases of the rare entity, uterine endolymphatic stromal myosis, were evaluated in a collaborative study by gynecologic oncologists trained at the M, D. Anderson Tumor Institute. Fifty percent developed recurrent disease subsequent to initial surgical therapy. Of the surgical stage I cases, 47% developed pelvic recurrences, and 9% developed distant recurrences only after initial therapy. The five- and ten-year life-table survival of surgical stages I to IV were 88% for stage I, 66% for stage II, 100% for stage III, and 75% for stage IV. These long-term survival rates were due in part to the hormonal sensitivity of the recurrent tumors. Because of the high recurrence rate after initial therapy, a suggested plan of therapy is presented for patients with uterine endolymphatic stromal myosis.

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				P. Baker and E. Oliva Endometrial stromal tumours of the uterus: a practical approach using conventional morphology and ancillary techniques J. Clin. Pathol., March 1, 2007; 60(3): 235 - 243. [Abstract] [Full Text] [PDF]