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Obstetrics & Gynecology 1984;63:S66
© 1984 by The American College of Obstetricians and Gynecologists
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Merkel Cell Carcinoma of the Vulva

KENT BOTTLES, MD, CONLEY G. LACEY, MD, JAMES GOLDBERG, MD, KATARINA LANNER-CUSIN, MD, JOANNE HOM, MD and THEODORE R. MILLER, MD

Departments of Pathology and Obstetrics, Gynecology, and Reproductive Sciences, University of California School of Medicine, San Francisco, California.

Abstract

The authors describe the clinical and histologic findings in a case of Merkel cell carcinoma of the vulva, which was associated with squamous cell carcinoma in situ and lichen sclerosus. Electron microscopy of the tumor revealed membrane-bound granules. At postmortem examination, metastases from this primary skin tumor were found in the pelvic lymph nodes, in paraortic lymph nodes, in the liver, and in vertebral bodies. The case is unusual because Merkel cell tumors are usually found on the face or the extremities and seldom metastasize widely.







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