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From the Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, and the Department of Surgery, Division of Plastic Surgery, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, Pennsylvania.
Abstract
A case of spontaneous synergistic bacterial gangrene occurring after external pelvic irradiation is presented in a 25-year-old woman with invasive cervical cancer. Treatment consisted of aggressive antibiotic therapy and extensive excision and debridement followed by split-thickness skin grafting. Both recovery and cosmetic results were satisfactory. The pathophysiology, predisposing factors, and treatment modalities are presented.
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