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From the Department of Obstetrics and Gynaecology, University of Western Australia, King Edward Memorial Hospital; and PIVET Laboratory, Subiaco, Perth, Western Australia.
Abstract
Three cases of combined pregnancy are described after gonadotropin therapy; two cases after human pituitary gonadotropin and one after human menopausal gonadotropin administration. In each case the intrauterine gestation was a multiple pregnancy. After salpingectomy, two of the women have proceeded to the delivery of healthy infants; the third woman aborted. In each case the gonadotropin stimulation regimen was ceased at the appropriate stage when the estriol excretion was between 60 and 125 µg/day, but the subsequent rate of rise of estriol was 2.3– to 3.2-fold during the coasting phase before the human chorionic gonadotropin trigger when the estriol excretion rate was 140 to 350 µg/day.
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