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Obstetrics & Gynecology 1984;63:463-466
© 1984 by The American College of Obstetricians and Gynecologists
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Lymphocyte Subsets in Endometriosis

NORBERT GLEICHER, MD, W P DMOWSKI, MD, PhD, ISRAEL SIEGEL, PhD, TIAN L. LIU, MD, JAN FRIBERG, MD, PhD, EWA RADWANSKA, MD and VLADIMIR TODER, MD, PhD

From the Departments of Obstetrics and Gynecology, Mount Sinai Hospital Medical Center of Chicago, Presbyterian St. Luke's Medical Center, and Rush Medical College, Chicago, Illinois

Abstract

Recent investigations suggested a possible immunologic etiology for endometriosis. To determine whether cellular immunity may be affected in patients with endometriosis, peripheral lymphocyte populations were investigated in 31 confirmed endometriosis patients and 22 control patients. No statistical differences in OKT3, OKT4, OKT8, OKM1, and OKTal cells could be observed. Total lymphocyte numbers were within normal ranges for both groups. Helper/suppressor ratios were not statistically different and were in a normal range for both groups. It is concluded that numeric differences in lymphocyte subpopulations represent only a very unlikely contributing factor in a potential immunologic etiology of endometriosis.




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K. Ishii, K. Takakuwa, T. Mitsui, and K. Tanaka
Studies on the human leukocyte antigen-DR in patients with endometriosis: genotyping of HLA-DRB1 alleles
Hum. Reprod., March 1, 2002; 17(3): 560 - 563.
[Abstract] [Full Text] [PDF]


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