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Obstetrics & Gynecology 1984;63:360-364
© 1984 by The American College of Obstetricians and Gynecologists
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Prenatal Diagnosis of Skeletal Dysplasia by Real-Time Ultrasound

J. W. WLADIMIROFF, MD, M. F. NIERMEIJER, MD, J. LAAR, M. JAHODA, MD and P. A. STEWART

Departments of Obstetrics and Cynecology and of Clinical Genetics, Erasmus University, Rotterdam, The Netherlands.

A control group of 165 normal pregnant women between 16 and 22 weeks' gestation was studied by real-time ultrasound scan to establish the normal length of the femur, tibia–fibula complex, humerus, and radius-ulna complex. A group of 32 pregnant women at risk for various types of fetal skeletal dysplasia were studied during the same gestational period. In three cases a structural defect was diagnosed, resulting in elective abortion. Conditions for optimal prenatal diagnosis of skeletal dysplasias are discussed.






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Copyright © 1984 by the American College of Obstetricians and Gynecologists.