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Obstetrics & Gynecology 1984;63:140-144
© 1984 by The American College of Obstetricians and Gynecologists
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Repeat Gestational Trophoblastic Disease

PETER K. SAND, MD, JOHN R. LURAIN, MD and JOHN I. BREWER, MD, PhD1

1From the Trophoblastic Disease Center, The Department of Obstetrics and Cynecology, and the Cancer Center, Northwestern University Medical School and Northwestern Memorial Hospital, Chicago, Illinois

Abstract

During a ten-year period from 1969 through 1979, 22 of 1648 patients referred to the John I. Brewer Trophoblastic Disease Center of Northwestern University Medical School had repeat gestational trophoblastic disease, an incidence of 1.33%. A total of 52 trophoblastic disease episodes occurred in these 22 patients. Invasive mole or choriocarcinoma occurred as the first trophoblastic disease episode in only three patients (14%), whereas one of these sequelae was the second trophoblastic disease event in seven patients (32%). Seventeen patients (77%) had consecutive trophoblastic disease episodes. After a second trophoblastic disease episode, the risk for a subsequent event rose to 28%; however, 44% of these patients delivered viable infants. There was no difference in outcome of subsequent pregnancies with respect to previous chemotherapy.




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H. Matsui, Y. Iitsuka, K. Suzuka, K. Seki, and S. Sekiya
Subsequent pregnancy outcome in patients with spontaneous resolution of HCG after evacuation of hydatidiform mole: comparison between complete and partial mole
Hum. Reprod., June 1, 2001; 16(6): 1274 - 1277.
[Abstract] [Full Text] [PDF]


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Copyright © 1984 by the American College of Obstetricians and Gynecologists.