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Obstetrics & Gynecology 1984;63:115-120
© 1984 by The American College of Obstetricians and Gynecologists
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THE OBSTETRIC SIGNIFICANCE OF HOLOPROSENCEPHALY

Frank A. Chervenak, MD, Glenn Isaacson, MD, Maurice J. Mahoney, MD, Marge Tortora, RDMS, Thalia Mesologites, MD and John C. Hobbins, MD

From the Departments of Obstetrics and Gynecology, Pathology, and Human Genetics, Yale-New Haven Medical Center, New Haven, Connecticut

Abstract

The present study reviews the entity of holoprosencephaly as it relates to obstetric diagnosis and management. Classification, embryology, and etiology are summarized. Serial sonographic findings in a recent case of holoprosencephaly complicated by hydrocephalus are presented. Criteria for antenatal diagnosis and newborn recognition as well as an approach to management are proposed.




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 Journal of Diagnostic Medical SonographyHome page
D. E. Bogart and D. A. Wolf
Diagnostic Challenge
Journal of Diagnostic Medical Sonography, September 1, 1986; 2(5): 291 - 293.
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Copyright © 1984 by the American College of Obstetricians and Gynecologists.