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Obstetrics & Gynecology 1983;61:755-757
© 1983 by The American College of Obstetricians and Gynecologists
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RECURRENT ANAPHYLACTIC REACTION TO INTRAPERITONEAL DEXTRAN 75 USED FOR PREVENTION OF POSTSURGICAL ADHESIONS

Max Borten, MD, Carol P. Seibert, MD and Melvin L. Taymor, MD

From the Department of Obstetrics and Gynecology and the Department of Anesthesia, The Charles A. Dana Biomedical Research Institute, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts

Abstract

The use of intraperitoneal dextran at the conclusion of a gynecologic surgical procedure to prevent postoperative adhesions has increased recently. Although anaphylactic reaction to dextran administered intravenously is well documented, the authors report such a reaction after intraperitoneal administration. The delayed appearance and the continuation of the undesirable reaction until the intraperitoneal reservoir of dextran was removed by means of a culdocentesis are noteworthy. Physicians should be alerted to this potential complication.






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Copyright © 1983 by the American College of Obstetricians and Gynecologists.