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Obstetrics & Gynecology 1983;61:733-736
© 1983 by The American College of Obstetricians and Gynecologists
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Intraamniotic Injection of Ethacridine for Second-Trimester Induction of Labor

KAI-HUI TIEN, MD

From the Division of Clinical Research, Hunan Provincial Research Institute on Family Planning, Changsha, People's Republic of China

Abstract

In the People's Republic of China one of the most widely used methods of second-trimester abortion is the intraamniotic injection of ethacridine (Rivanol). Intraamniotic ethacridine produces fetal death, a fall in maternal urinary estriol excretion, and a rise in prostaglandin levels. Although the induction time is longer than that usually seen with prostaglandins, the method is not ordinarily associated with vomiting, cervical injury, or the delivery of a live fetus. In a series of 10,302 cases, the success rate was 96.4% and the incidence of associated complications was low.






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