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Carcinogenic Potential Of In Vitro Carbon Dioxide Laser Exposure Of Fibroblast

From the Comprehensive Laser Center, Palo Alto Medical Foundation, Palo Alto, California

Increasing clinical use of the CO₂ laser in gynecology has been valuable for both external genital and internal reproductive problems. Long-term safety effects of the CO₂ laser are investigated in the present study. Fibroblasts grown in tissue culture were exposed to the CO₂ laser. They were then grown for nine future generations and scored for possible malignant transformation. Results of the study show that the CO₂laser does not produce a greater incidence of malignant transformation than normal controls. Therefore, in laboratory cells, the CO₂ laser appears to be noncarcinogenic.