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Perinatal Infection With Torulopsis Glabrata: A Case Associated With Maternal Sickle Cell Anemia

From the Placetital Tissue Registry, Department of Pathology and Department of Microbiology and Public Health, Michigan State University, East Lansing, Michigan; and the Departments of Obstetrics and Gynecology, Pediatrics, and Pathology, the University of Michigan Medical Center, Ann Arbor, Michigan

Abstract

Torulopsis glabrata is a yeast of low virulence and commensal within the female genitourinary tract. The first case of congenital infection with Torulopsis glabrata was reported in 1980. An additional example of perinatal Torulopsis infection which is associated with maternal sickle cell anemia is reported. The most common source of congenital fungus infection is Candida albicans. Differences in morphology between T glabrata and C albicans are apparent, particularly the pathologic response within the placenta. Pathogenicity in this case may be associated with increased susceptibility to infection in patients with sickle cell anemia. (Obstet Gynecol 61:21S, 1983)