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Obstetrics & Gynecology 1983;61:63-74
© 1983 by The American College of Obstetricians and Gynecologists
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Carcinoma of the Vulva: Analysis of Treatment and Survival

KARL C. PODRATZ, MD, PhD, TIFFANY J. WILLIAMS, MD and WILLIAM F. TAYLOR, PhD

From the Mayo Clinic and Mayo Foundation, Rochester, Minnesota

Abstract

The treatment of 224 patients with invasive squamous cell carcinoma of the vulva over a 20-year interval at the Mayo Clinic resulted in an overall survival rate of 75%, compared with 89% for age-matched controls. For patients with stage I disease, 5-year survival was 90%; for those with stages II, III, and IV, it was 81, 68, and 20%, respectively. A precipitous decline in survival rates was noted when metastases to regional nodes were encountered, when lesion size was more than 3 cm, arid when histologic dedifferentiation exceeded grade 2. Incorrect clinical staging efforts were observed in 25% of the cases, so the necessity for surgical staging was apparent.




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Copyright © 1983 by the American College of Obstetricians and Gynecologists.