HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by DeVORE, G. R. Articles by KASE, N. Search for Related Content PubMed PubMed Citation Articles by DeVORE, G. R. Articles by KASE, N.

Use of Intravenous Premarin® in the Treatment of Dysfunctional Uterine Bleeding—A Double- Blind Randomized Control Study

From the Department of Obstetrics and Gynecology, Yak University School of Medicine, New Haven, Connecticut

Abstract

Dysfunctional uterine bleeding results from disruption of the normal sequence of ovarian cyclic hormonal stimulation of the uterine endometrium. Treatment of dysfunctional uterine bleeding previously consisted of surgical or hormonal manipulation, or both. The present study was conducted on 34 patients in a randomized double-blind fashion to evaluate the efficacy of treating dysfunctional uterine bleeding with intravenous Premarin. Bleeding stopped in 72% of patients who received intravenous Premarin and in 38% who received placebo (P=.021). Premarin was effective in terminating endometrial bleeding in patients with biopsyproved pathology consisting of secretory, proliferative, menstrual, polypoid, or cystic hyperplasia, as well as endometritis.

This article has been cited by other articles:

				M. G. Munro, N. Mainor, R. Basu, M. Brisinger, and L. Barreda Oral medroxyprogesterone acetate and combination oral contraceptives for acute uterine bleeding: a randomized controlled trial. Obstet. Gynecol., October 1, 2006; 108(4): 924 - 929. [Abstract] [Full Text] [PDF]