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Obstetrics & Gynecology 1981;57:661-665
© 1981 by The American College of Obstetricians and Gynecologists
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SUCCESSFUL TREATMENT OF POLYCYSTIC OVARY SYNDROME WITH SPIRONOLACTONE OR BROMOCRIPTINE

Ilana Blum, MD, Hayuta Kaufman, PhD, Raphael Marilus, MD, Yael Rusecki, MD and Israel Chovers, MD

From the Departments of Internal Medicine B and of Endocrinology and the Endocrinological Laboratories, Beilinson Medical Center, Petah Tiqva, The Sackler School of Medicine, Tel Aviv University, Ramat Aviv, Israel

Abstract

Marked improvement in the severe hypertension (250/150 mmHg) and hirsutism of a patient suffering from polycystic ovary syndrome was quickly achieved by the use of spironolactone 200 mg per day. Substitution of spironolactone with bromocriptine induced further amelioration of these symptoms and renewal of ovulatory cycles. These drugs may afford another mode of therapy in patients with polycystic ovary syndrome.






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