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SINGLE-DOSE METRONIDAZOLE TREATMENT FOR VAGINAL TRICHOMONIASIS

From the Medical Department, Federal Reformatory for Women, Alderson, West Virginia

Incoming inmates to a female prison, with a 47% prevalence of trichomonas vaginitis, were treated with a single 2-g dose of metronidazole. Follow-up of 237 patients revealed a cure rate of 97%. Four patients in whom initial treatment failed responded to repeat single-dose treatment. Significant side reactions were not encountered. Treatment noncompliance was reduced from approximately 25% to zero. The cost of the trichomoniasis treatment program was reduced by approximately 60%. The simplicity and the reduced cost associated with the single-dose treatment regimen should reduce patient and consort therapeutic noncompliance and is a significant improvement over the currently recommended 7-day treatment regimen. (Obstet Gynecol 56:508, 1980)

This article has been cited by other articles:

				J. R. Schwebke and D. Burgess Trichomoniasis Clin. Microbiol. Rev., October 1, 2004; 17(4): 794 - 803. [Abstract] [Full Text] [PDF]