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Obstetrics & Gynecology 1978;52:46-49
© 1978 by The American College of Obstetricians and Gynecologists
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The Estriol /Creatinine Ratio in a Random Urine Sample as a Screening Test

C J HUTCHINS, MD

From the National Women's Hospital, Auckland, New Zealand.

Abstract

The estriol/creatinine ratio was determined in a first morning urine sample in 1808 pregnancies in the 32nd week of gestation. The ratio obtained correlated closely with birthweight and showed a linear increase with percentile birthweight group. There was a 25-fold increase in perinatal mortality in those pregnancies with a ratio below the tenth percentile; all pregnancies ending in stillbirths with birthweight below the tenth percentile gave such a ratio. The single estrogen/creatinine ratio allowed the early detection of a group of pregnancies at high risk of intrauterine growth retardation or major total abnormality without inconvenience for the patient.






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Copyright © 1978 by the American College of Obstetricians and Gynecologists.