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Obstetrics & Gynecology 1978;52:125-127
© 1978 by The American College of Obstetricians and Gynecologists
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AMNIOTIC FLUID COPPER AND ZINC CONCENTRATIONS IN HUMAN PREGNANCY

Ronald A. Chez, MD, FA COG, Robert I. Henkin, MD and Rosemary Fox, MS

From the Nalional Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, and the Departments of Obstetrics and Gynecology at Georgetown University School of Medicine, Washington, D.C., and the University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

Amniotic fluid concentrations of zinc and copper were measured in human pregnancy of 12 to 44 weeks' gestation. Although mean values for both metals are relatively flat throughout pregnancy, there appears to be a relative increase in copper levels between 26 and 33 weeks' gestation, and increasing levels of zinc after 34 weeks. Correlations with fetal age or fetal-maternal disease are not apparent in specimens from this heterogenous population.







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