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From the Department of Gynecology and Obstetrics, Registry for Liver Tumors Associated with Oral Contraceptives, at University of California, Irvine School of Medicine, Irvine, California.
Abstract
Four cases of liver adenoma associated with oral contraceptives complicating pregnancy are reported. All patients were symptomatic during pregnancy and 2 were admitted with rupture of the adenoma. One subsequently died. Increased growth and vascularity of adenomas during pregnancy is highly likely. The potential for development of lethal complications is considerable.
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