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Obstetrics & Gynecology 1978;51:97-100
© 1978 by The American College of Obstetricians and Gynecologists
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Endometrial Adenocarcinoma and the Stein-Leventhal Syndrome

KIANOOSH JAFARI, MD, FACOG, GHODRATOLLAH JAVAHERI, MD, FACOG and GUSTAVO RUIZ, MD

From the Departments of Obstetrics and Gynecology at Cook County Hospital, the University of Health Sciences/The Chicago Medical School, Michael Reese Hospital and the University of Chicago, Chicago, Illinois.

Six cases of adenocarcinoma of the endometrium associated with the Stein-Leventhal syndrome are presented. The average age of the patients was 27.8 years. All patients were treated surgically; 2 had preoperative intracavitary irradiation, and 1 had postoperative intravaginal cesium-137 application. At followup, ranging from 1 to 15 years, all patients are alive and free of disease. Almost 90% of endometrial adenocarcinoma in association with the Stein-Leventhal syndrome is well differentiated, and appropriate treatment is associated with a good prognosis. Conservative therapy carries the risk of progression of the cancer to more advanced stages and has very little to offer for future fertility. It is suggested that these patients be treated as are any other patients with endometrial cancer.




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