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PROLACTIN HYPERSECRETION AND SHORT LUTEAL PHASE DEFECTS

From the Departments of Medicine. Obstetrics and Gynecology at Toronto General Hospital, Toronto, Ontario. Canada

Abstract

The short Iuteal phase defect is commonly found in ovulating women presenting with infertility, or in amenorrheic women induced to ovulate with clomiphene. When the short luteal phase defect is accompanied by the discovery of galactorrhea, the two abnormalities may share a common underlying cause. Two cases are presented to demonstrate the short Iuteal phase defect as one early manifestation that may occur during the development of the amenorrhea-galactorrhea syndrome. Antiprolactin therapy may cause this menstrual disorder to revert to normal, allowing normal fertility and terminating the galactorrhea.