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Obstetric Observations in Eleven Cases of Neonatal Sepsis Due to the Group B ß Hemolytic Streptococcus

From the Department of Obstetrics and Gynecology at the University of Southern California School of Medicine. Los Angeles. California

Abstract

Neonatal sepsis due to Group B streptococcus is reported to be increasing, but tbe reasons are unclear. Eleven cases from a single hospital Here reviewed for common obstetric factors. Frequent observations associated with 8 surviving infants were maternal infection, early evaluation and treatment of the newborn, and 4 + or 5+ growth on maternal cultures. In contrast, mothers of the 3 infants who died hud no clinical signs of infection, and cultures were not obtained. All 11 infants had direct monitoring during labor but the frequency of infection, 1/1600 live births, was lower than usually reported. Three surviving infants and 3 nonsurvivors were premature. Semiquantilative culture technics suggest that the predominance of Group B streptococcus in the vagina may be a more important etiologic factor than the frequency of its presence.