HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by SINGLEY, T. Articles by GANT, N F Search for Related Content PubMed PubMed Citation Articles by SINGLEY, T. Articles by GANT, N F

Metabolic Clearance Rate of Dehydroisoandrosterone Sulfate

VII. Effect of Lateral Versus Supine Recumbency

From the Cecil H. and Ida Green Center for Reproductive Biology Sciences and Department of Obstetrics and Gynecology ut The University of Texas Southwestern Medical School. Dallas. Texas

Abstract

The physiologic events which may occur with the gravid woman in the supine position suggest that uteroplacental blood flow may be impaired as a consequence of decreased venous return to the heart and the resulting decrease in cardiac output. Since the metabolic clearance rate of dehydroisoandrosterone sulfate (MCR_DS) previously has been shown to reflect alterations in uteroplacental perfusion, the MCR_DS was measured in a variety of different obstetric conditions during lateral and supine recumbency. No significant difference in the MCR_DS was induced by this specific positional change, suggesting that ulcroplacental perfusion was not altered. Experimental data are discussed which support this observation, and a possible mechanism for maintenance of uteroplacental blood flow under these circumstances is presented.