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Obstetrics & Gynecology 1976;47:383-387
© 1976 by The American College of Obstetricians and Gynecologists
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Ovarian and Adrenal Steroid Production in the Postmenopausal Woman

ROBERT B. GREENBLATT, MD, FACOG, MICHEL L. COLLE, MD and VIRENDRA B. MAHESH, PhD

From the Department or Endocrinology at Medical College of Georgia, Augusta, Georgia, and Southeastern Research Foundation

Abstract

Relative contribution of the ovaries and adrenals to the pool of steroids in postmenopausal women is still the subject of much controversy. Estradiol, >4-androstenedione, and testosterone were assayed in peripheral blood, adrenal, and ovarian vein blood of II postmenopausal patients. Intravenous administration of hCG resulted in increased androgen production by the ovaries but not estrogens while intravenous administration of adrenocorticotrophic hormone did not result in the enhancement of ovaria and adrenal estrogens.




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Copyright © 1976 by the American College of Obstetricians and Gynecologists.