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Obstetrics & Gynecology 1976;47:337-341
© 1976 by The American College of Obstetricians and Gynecologists
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Clostridium perfringens Infection Complicating Chemotherapy for Choriocarcinoma

CONLEY G. LACEY, MD, FACOG, ROBERT FUTORAN, MD, FACOG and C. PAUL MORROW, MD, FACOG

Department of Obstetrics and Gynecology at the University of Southern California Medical Center, Los Angeles, California.

A case of Clostridium perfringens sepsis and gas gangrene complicating chemotherapy for gestational choriocarcinoma is reported. The infection was eradicated using antibiotics, surgery, and hyperbaric oxygen therapy. The pathophysiology, diagnosis, and treatment of this unusual but often lethal complication are reviewed.






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