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Department of Endocrinology, Medical College of Georgin, Augusta, Georgia
Abstract
The olfacto-genital syndrome (Kallman's syndrome) is believed to be primarily an hypolhalamic disorder resulting in hypogonadotropic hypogonadism or hypo-ovarianism and anosmia. The pituitary response in 2 patients was measured on daily subcutaneous injections of 100 µg of LHRF. One of the patients was also studied in a similar fashion by administration of LHRF intravenously for 4 consecutive days. A greater response occurred with the subcutaneous route.
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