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Obstetrics & Gynecology 1976;47:210-212
© 1976 by The American College of Obstetricians and Gynecologists
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The Possible Deleterious Effects of the Intramyometrial Injection of Hypertonic Urea

TIM H. PARMLEY, MD, FACOG, LQNNIE S. BURNETT, MD, FACOG, DAVID A. BLAKE, PhD, BARBARA C. MIYASAKI, BS and THEODORE M. KING, MD, FACOG

Department of Obstetrics and Gynecology and the Gynecologic Pathology Laboratory of The Johns Hopkins Hospital, Baltimore, Maryland.

Hypertonic urea has been shown to be an effective midtrimester abortifacient. Although safer than hypertonic saline when injected intravascularly, it has not been compared to saline in the case of inadvertent intramyometrial injection. This report document that intramyometrial injection of hypertonic urea will result in the same type of muscle necrosis as that produced by saline.






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Copyright © 1976 by the American College of Obstetricians and Gynecologists.