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Obstetrics & Gynecology 1976;47:63
© 1976 by The American College of Obstetricians and Gynecologists
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Topical 5-Fluorouracil in the Treatment of Carcinoma in Situ of the Vulva

THOMAS E. CARSON, Capt, MC, USN, WILLIAM J. HOSKINS, LCDR, MC, USN and JOHN F. WURZEL, Capt, MC, USN

From the Departments of Dermatology and Obstetrics and Gynecology, Naval Regional Medical Center, Oakland, California.

The clinical and pathologic response of carcinoma in situ of the vulva in a 42-year-old woman treated with topical 5-fluorouracil is reported. Except for one persistent area of involvement in the anal region which required local excision, the result of treatment was excellent, with no evidence of recurrence after 2 years' followup. This important adjunct in the treatment of intra-epithelial carcinoma deserves long-range investigation.






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Copyright © 1976 by the American College of Obstetricians and Gynecologists.