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Obstetrics & Gynecology 1976;47:80-82
© 1976 by The American College of Obstetricians and Gynecologists
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Serum FSH and Synthetic LHRH Response in Pregnant Women at Term and in the Newborn

JORGE SORIA, MD, PhD, ARTURO ZARATE, MD, ELIAS S. CANALES, MD, FACOG, FRANCISCO ARCOVEDO, MD and JORGE A. GONZALEZ, MD

From the Departments of Gynecologic Endocrinology and Pediatrics. Hospital Gineco Obstetricia No. Uno, Instituto Mexicano del Seguro Social, Mexico

Abstract

Serum immunoreactive FSH was undetectable in a) pregnant women past 38 weeks or gestation, b) newborn infants, and c) anencephalic infants. The intravenous administration of 100g of synthetic LHRH elicited no FSH release in each instance. These results seem to indicate that the absence of FSH in serum in pregnant women in the last trimester, as well as in the newborn, is due to the suppressive effect on the anterior pituitary of the increased amount of circulating sex steroids.







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